James has been ruled out after a scan on a hamstring problem, while Mount has a pelvic injury.
“Reece had a hamstring injury in the midweek game,” added Lampard. “He got through it but then had a scan and he’s out.
“Mason has been carrying a pelvic injury for a while. It predates myself and he has been trying typically but he will have minor surgery, then a four-week recovery.
“He [Mount] might make the last match but that’s unlikely, which is obviously disappointing for us.”